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93544ESRecombinant Human 4-1BB/TNFRSF9(His Tag)
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產(chǎn)品簡(jiǎn)介
| 供貨周期 | 兩周 | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,生物產(chǎn)業(yè) |
|---|
產(chǎn)品介紹
產(chǎn)品信息
產(chǎn)品名稱 | 產(chǎn)品編號(hào) | 規(guī)格 |
Recombinant Human 4-1BB/TNFRSF9 (His Tag) | 93544ES25 | 25 μg |
93544ES60 | 100 μg | |
93544ES76 | 500 μg | |
93544ES80 | 1 mg |
產(chǎn)品描述
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
產(chǎn)品性質(zhì)
別名（Synonyms） | CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA |
Uniprot No. | Q07011 |
表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source） | HEK293 Cells-derived Human 4-1BB/TNFRSF9 Protein, Leu24-Gln186 with His tag at the C-terminal |
分子量(Molecular Weight) | Approximately 18.1 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result. |
外觀(Physical Appearance） | Sterile Filtered White lyophilized (freeze-dried) powder. |
純度（Purity） | > 95% as determined by SDS-PAGE and HPLC |
活性（Activity） | ELISA Data: Immobilized Human 4-1BB, His Tag at 1μg/mL (100 μL/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 5.7 ng/mL determined by ELISA. |
內(nèi)毒素（Endotoxin） | < 1.0 EU per 1μg of the protein by the LAL method. |
制劑（Formulation） | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
復(fù)溶（Reconstitution） | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water. |
運(yùn)輸與保存方法
冰袋運(yùn)輸。-20℃至-80℃保存，一年有效期。
復(fù)溶后，-20 至 -80°C，在未開封狀態(tài)下保存 3-6 個(gè)月。復(fù)溶后，2-8°C 保存 2-7 天。
建議第一次使用時(shí)分裝凍存，避免反復(fù)凍融。
注意事項(xiàng)
避免反復(fù)凍融。
為了您的安全和健康，請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
本產(chǎn)品僅作科研用途！
產(chǎn)品數(shù)據(jù)
Tris-Bis PAGE
SEC-HPLC
ELISA Data
